ASH 2009 meeting report- the top 10 clinically-oriented abstracts in chronic lymphocytic leukemia (CLL)
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Canadian CLL Meeting 2015 Anti-Malarial Drugs Disrupt Lysosomes in Chronic Lymphocytic Leukemia (CLL) Cells
CLL is the most common type of leukemia in the Western world and represents the most common cause of secondary immunodeficiency which can benefit from immunoglobulin replacement therapy (IgRT). While immunoglobulin replacement therapy is usually administered intravenously in a hospital or outpatient facility, the availability of subcutaneous (SCIg) administration is often very appreciated by pa...
متن کاملCHRONIC LYMPHOCYTIC LEUKEMIA Treatment algorithms in CLL
CLL therapy has changed dramatically over the last few years. This development has been aided by progress in 2 areas: (1) a better understanding of CLL biology (and with it discovery and characterization of new prognostic markers); and (2) emergence of novel agents. The combined impact of advances in these areas is leading to new concepts and approaches in CLL therapy. Treatment of CLL has been...
متن کاملChronic Lymphocytic Leukemia (CLL) — Staging and Prognosis
Chronic lymphocytic leukemia (CLL) affects the B-cells of the immune system and is, as the most common leukemia in adults, an important hematological differential diagnosis. It often hardly progresses for years and therefore a CLL does not always need immediate therapy. In the past years especially, a lot has happened with regard to diagnostic options and treatment, so that being informed about...
متن کاملMore ZAP for chronic lymphocytic leukemia (CLL).
Antigen stimulation of the leukemic clone is increasingly implicated in the pathogenesis of CLL. Chen and colleagues provide evidence that expression of ZAP-70 in CLL B cells renders IgM signaling more effective and thereby could contribute to the more rapidly progressive clinical course of ZAP-70-positive CLL.
متن کاملChronic Lymphocytic Leukemia (CLL) — Staging and Prognosis
Chronic lymphocytic leukemia (CLL) affects the B-cells of the immune system and is, as the most common leukemia in adults, an important hematological differential diagnosis. It often hardly progresses for years and therefore a CLL does not always need immediate therapy. In the past years especially, a lot has happened with regard to diagnostic options and treatment, so that being informed about...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2010
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.21640